Autophagy and senescence of rat retinal precursor cells under high glucose
BackgroundsDiabetic retinopathy (DR) is a common diabetic ocular disease characterized by retinal ganglion cell (RGC) changes.An abnormal environment, hyperglycemia, may progressively alter the structure and function of RGCs, which is a primary pathological feature of retinal neurodegeneration in DR.Accumulated studies confirmed autophagy and senes